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W Thomson Selected Research

Rheumatoid Arthritis

1/2017Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
1/2014HLA-DRB1 associations with rheumatoid arthritis-related pulmonary fibrosis.
6/2013Genetic polymorphisms in key methotrexate pathway genes are associated with response to treatment in rheumatoid arthritis patients.
4/2013MTHFR gene polymorphisms and outcome of methotrexate treatment in patients with rheumatoid arthritis: analysis of key polymorphisms and meta-analysis of C677T and A1298C polymorphisms.
4/2011HLA-DPB1-COL11A2 and three additional xMHC loci are independently associated with RA in a UK cohort.
12/2010Testing pharmacogenetic indices to predict efficacy and toxicity of methotrexate monotherapy in a rheumatoid arthritis patient cohort.
1/2009Can clinical factors at presentation be used to predict outcome of treatment with methotrexate in patients with early inflammatory polyarthritis?
1/2009Association of rheumatoid factor and anti-cyclic citrullinated peptide positivity, but not carriage of shared epitope or PTPN22 susceptibility variants, with anti-tumour necrosis factor response in rheumatoid arthritis.
5/2008Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis.
10/2007The pharmacogenetics of methotrexate.
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W Thomson Research Topics

Disease

21Rheumatoid Arthritis
01/2017 - 04/2000
9Arthritis (Polyarthritis)
01/2018 - 07/2000
9Juvenile Arthritis (Juvenile Idiopathic Arthritis)
01/2018 - 04/2001
5Giant Cell Arteritis (Horton Disease)
05/2002 - 08/2000
4Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis)
03/2002 - 08/2000
3Systemic Lupus Erythematosus (Libman-Sacks Disease)
10/2001 - 05/2001
2Necrosis
01/2009 - 05/2006
2Psoriasis (Pustulosis Palmaris et Plantaris)
05/2008 - 07/2000
2Neoplasms (Cancer)
05/2007 - 01/2001
2Disease Susceptibility (Diathesis)
05/2006 - 06/2001
2Vasculitis (Vasculitides)
07/2002 - 05/2001
2Purpura
06/2001 - 05/2001
1AIDS-Related Complex (ARC)
09/2015
1Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2014
1Synovitis
10/2010
1Autoimmune Diseases (Autoimmune Disease)
03/2010
1Joint Diseases (Joint Disease)
02/2009
1Genetic Predisposition to Disease (Genetic Predisposition)
01/2009
1Keloid
08/2008
1Dupuytren Contracture (Dupuytrens Contracture)
08/2008
1Cicatrix (Scar)
08/2008
1Psoriatic Arthritis
05/2008
1Myocardial Ischemia (Ischemic Heart Diseases)
05/2007
1Uveitis
08/2006
15 Insulin-Dependent Diabetes Mellitus
11/2005
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
11/2005
1Acute-Phase Reaction
08/2005
1Dog Diseases (Disease, Canine)
01/2005
1Infections
03/2002
1Erythema Nodosum
12/2001
1Sarcoidosis (Schaumann Disease)
12/2001
1Disease Progression
10/2001
1Invasive Pulmonary Aspergillosis
09/2001
1Anemia
07/2001
1Multiple Sclerosis
04/2001
1Sjogren's Syndrome (Sjogren Syndrome)
11/2000
1Spondylarthritis (Spinal Arthritis)
07/2000
1Pain (Aches)
07/2000
1Fever (Fevers)
07/2000
1Osteoporosis
01/2000

Drug/Important Bio-Agent (IBA)

20HLA-DRB1 Chains (HLA DRB1)IBA
01/2017 - 04/2000
7Methotrexate (Mexate)FDA LinkGeneric
08/2014 - 10/2007
6Rheumatoid FactorIBA
01/2018 - 07/2000
6EpitopesIBA
01/2009 - 04/2000
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2006 - 04/2000
2Amino AcidsFDA Link
01/2017 - 02/2001
2AntibodiesIBA
01/2009 - 09/2007
2cyclic citrullinated peptideIBA
01/2009 - 09/2007
2HLA-DRB1*04 antigenIBA
05/2008 - 07/2001
2CytokinesIBA
05/2006 - 04/2001
2Macrophage Migration-Inhibitory FactorsIBA
10/2003 - 08/2001
2Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
09/2001 - 09/2001
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
07/2001 - 05/2001
2HLA-DR Antigens (HLA-DR)IBA
12/2000 - 04/2000
1Genetic Markers (Genetic Marker)IBA
04/2012
1CCR5 Receptors (CCR5 Receptor)IBA
10/2010
1interleukin-21 (interleukin 21)IBA
03/2010
1Interleukin-2 (IL2)IBA
03/2010
1Antirheumatic Agents (DMARD)IBA
01/2009
1HLA-DRB1*07 antigenIBA
05/2008
1Anti-Citrullinated Protein AntibodiesIBA
09/2007
1Methionine (L-Methionine)FDA Link
11/2005
1Valine (L-Valine)FDA Link
11/2005
1AutoantibodiesIBA
08/2005
1Toll-Like Receptor 4IBA
05/2005
1DNA (Deoxyribonucleic Acid)IBA
01/2005
1HLA-A Antigens (HLA-A)IBA
09/2004
1Discoidin Domain Receptor 1IBA
09/2004
1E-SelectinIBA
07/2002
1Interleukin-1 (Interleukin 1)IBA
05/2002
1Interleukin-6 (Interleukin 6)IBA
03/2002
1Corticotropin-Releasing HormoneIBA
03/2002
1VaccinesIBA
03/2002
1ProlactinIBA
10/2001
1Fc gamma receptor IIAIBA
09/2001
1Codon (Codons)IBA
05/2001
1Aspartic Acid (Aspartate)FDA Link
02/2001
1AntigensIBA
12/2000
1Antinuclear AntibodiesIBA
07/2000
1Alendronate (Alendronate Sodium)FDA LinkGeneric
01/2000

Therapy/Procedure

3Therapeutics
01/2009 - 01/2001
1Synchrotrons
09/2015